P30281 (P30281)

Overview
Predicted structure (AF):
AF-P30281-F1-model_v4
Uniprot entry:
P30281
Gene:
P30281
Protein length:
292 residues
Mutations found:
5547
Benign based on D2Deep prediction:
3019 out of 5547 mutations
Pathogenic based on D2Deep prediction:
2528 out of 5547 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5547 mutations across 292 unique positions. There are 3019 benign and 2528 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 A 18 1 19 0.097 0.541 View mutations
177 L 19 0 19 0.058 0.447 View mutations
178 V 7 12 19 0.598 0.529 View mutations
179 K 17 2 19 0.120 0.429 View mutations
180 K 2 17 19 0.902 0.603 View mutations
181 H 16 3 19 0.286 0.339 View mutations
182 A 10 9 19 0.426 0.485 View mutations
183 Q 14 5 19 0.285 0.403 View mutations
184 T 1 18 19 0.919 0.750 View mutations
185 F 8 11 19 0.542 0.553 View mutations
186 L 16 3 19 0.198 0.333 View mutations
187 A 9 10 19 0.547 0.512 View mutations
188 L 2 17 19 0.880 0.726 View mutations
189 C 0 19 19 0.971 0.784 View mutations
190 A 16 3 19 0.221 0.367 View mutations
191 T 2 17 19 0.895 0.674 View mutations
192 D 1 18 19 0.925 0.605 View mutations
193 Y 17 2 19 0.164 0.411 View mutations
194 T 8 11 19 0.597 0.511 View mutations
195 F 3 16 19 0.825 0.670 View mutations
196 A 19 0 19 0.020 0.314 View mutations
197 M 19 0 19 0.055 0.379 View mutations
198 Y 5 14 19 0.692 0.550 View mutations
199 P 19 0 19 0.119 0.175 View mutations
200 P 2 17 19 0.910 0.830 View mutations