P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
476 S 19 0 19 0.001 0.623 View mutations
477 A 17 2 19 0.156 0.540 View mutations
478 S 19 0 19 0.003 0.639 View mutations
479 I 13 6 19 0.288 0.572 View mutations
480 R 17 2 19 0.144 0.605 View mutations
481 E 6 13 19 0.607 0.376 View mutations