P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
451 T 19 0 19 0.001 0.406 View mutations
452 P 16 3 19 0.198 0.418 View mutations
453 P 19 0 19 0.002 0.517 View mutations
454 D 19 0 19 0.000 0.698 View mutations
455 R 19 0 19 0.023 0.749 View mutations
456 Y 17 2 19 0.093 0.749 View mutations
457 D 19 0 19 0.008 0.752 View mutations
458 S 19 0 19 0.001 0.771 View mutations
459 L 19 0 19 0.001 0.737 View mutations
460 G 19 0 19 0.000 0.762 View mutations
461 L 19 0 19 0.004 0.799 View mutations
462 L 19 0 19 0.001 0.722 View mutations
463 E 19 0 19 0.000 0.742 View mutations
464 L 19 0 19 0.000 0.765 View mutations
465 D 18 1 19 0.054 0.692 View mutations
466 Q 18 1 19 0.078 0.726 View mutations
467 R 16 3 19 0.195 0.604 View mutations
468 T 19 0 19 0.014 0.577 View mutations
469 H 17 2 19 0.105 0.563 View mutations
470 F 3 16 19 0.750 0.438 View mutations
471 P 15 4 19 0.261 0.475 View mutations
472 Q 19 0 19 0.002 0.475 View mutations
473 F 18 1 19 0.059 0.401 View mutations
474 S 19 0 19 0.023 0.409 View mutations
475 Y 16 3 19 0.128 0.485 View mutations