P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.039 0.710 View mutations
2 N 18 1 19 0.050 0.850 View mutations
3 E 9 10 19 0.486 0.460 View mutations
4 V 18 1 19 0.039 0.896 View mutations
5 S 19 0 19 0.003 0.880 View mutations
6 V 19 0 19 0.001 0.829 View mutations
7 I 19 0 19 0.000 0.707 View mutations
8 K 19 0 19 0.002 0.791 View mutations
9 E 19 0 19 0.005 0.707 View mutations
10 G 12 7 19 0.364 0.508 View mutations
11 W 19 0 19 0.002 0.686 View mutations
12 L 6 13 19 0.667 0.368 View mutations
13 H 19 0 19 0.061 0.803 View mutations
14 K 0 19 19 0.985 0.282 View mutations
15 R 19 0 19 0.087 0.568 View mutations
16 G 19 0 19 0.010 0.488 View mutations
17 E 2 17 19 0.854 0.412 View mutations
18 Y 4 15 19 0.758 0.417 View mutations
19 I 3 16 19 0.818 0.473 View mutations
20 K 15 4 19 0.253 0.409 View mutations
21 T 1 18 19 0.934 0.439 View mutations
22 W 14 5 19 0.267 0.444 View mutations
23 R 0 19 19 0.966 0.442 View mutations
24 P 3 16 19 0.711 0.397 View mutations
25 R 0 19 19 0.997 0.498 View mutations