P31751 (AKT2)

Overview
Predicted structure (AF):
AF-P31751-F1-model_v4
Uniprot entry:
P31751
Gene:
AKT2
Protein length:
481 residues
Mutations found:
9138
Benign based on D2Deep prediction:
5179 out of 9138 mutations
Pathogenic based on D2Deep prediction:
3959 out of 9138 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9138 mutations across 481 unique positions. There are 5179 benign and 3959 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
426 F 19 0 19 0.019 0.429 View mutations
427 K 8 11 19 0.555 0.434 View mutations
428 P 1 18 19 0.935 0.544 View mutations
429 Q 19 0 19 0.013 0.448 View mutations
430 V 17 2 19 0.130 0.390 View mutations
431 T 19 0 19 0.021 0.489 View mutations
432 S 9 10 19 0.481 0.433 View mutations
433 E 19 0 19 0.001 0.389 View mutations
434 V 15 4 19 0.225 0.431 View mutations
435 D 19 0 19 0.000 0.470 View mutations
436 T 19 0 19 0.000 0.386 View mutations
437 R 19 0 19 0.000 0.396 View mutations
438 Y 9 10 19 0.519 0.435 View mutations
439 F 16 3 19 0.180 0.465 View mutations
440 D 4 15 19 0.817 0.506 View mutations
441 D 15 4 19 0.242 0.483 View mutations
442 E 19 0 19 0.006 0.363 View mutations
443 F 19 0 19 0.010 0.445 View mutations
444 T 2 17 19 0.873 0.518 View mutations
445 A 18 1 19 0.074 0.444 View mutations
446 Q 19 0 19 0.006 0.452 View mutations
447 S 14 5 19 0.240 0.439 View mutations
448 I 18 1 19 0.070 0.361 View mutations
449 T 17 2 19 0.121 0.427 View mutations
450 I 17 2 19 0.095 0.468 View mutations