P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 17 1 18 0.063 0.581 View mutations
2 A 19 0 19 0.031 0.778 View mutations
3 T 16 3 19 0.231 0.728 View mutations
4 Q 14 5 19 0.245 0.669 View mutations
5 A 19 0 19 0.010 0.815 View mutations
6 D 19 0 19 0.002 0.843 View mutations
7 L 19 0 19 0.000 0.893 View mutations
8 M 19 0 19 0.000 0.910 View mutations
9 E 19 0 19 0.001 0.893 View mutations
10 L 19 0 19 0.001 0.936 View mutations
11 D 19 0 19 0.000 0.880 View mutations
12 M 19 0 19 0.007 0.943 View mutations
13 A 19 0 19 0.004 0.848 View mutations
14 M 19 0 19 0.007 0.952 View mutations
15 E 19 0 19 0.001 0.939 View mutations
16 P 16 3 19 0.104 0.795 View mutations
17 D 19 0 19 0.003 0.878 View mutations
18 R 19 0 19 0.004 0.946 View mutations
19 K 19 0 19 0.042 0.932 View mutations
20 A 19 0 19 0.006 0.857 View mutations
21 A 18 1 19 0.102 0.774 View mutations
22 V 19 0 19 0.004 0.754 View mutations
23 S 18 1 19 0.121 0.848 View mutations
24 H 16 3 19 0.165 0.677 View mutations
25 W 0 19 19 0.995 0.296 View mutations