P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
776 W 15 4 19 0.203 0.475 View mutations
777 F 8 11 19 0.620 0.432 View mutations
778 D 3 16 19 0.826 0.448 View mutations
779 T 13 6 19 0.332 0.455 View mutations
780 D 9 10 19 0.478 0.432 View mutations
781 L 8 11 19 0.509 0.434 View mutations