P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 N 14 5 19 0.242 0.715 View mutations
52 P 17 2 19 0.171 0.887 View mutations
53 E 16 3 19 0.197 0.782 View mutations
54 E 19 0 19 0.007 0.876 View mutations
55 E 19 0 19 0.000 0.836 View mutations
56 D 19 0 19 0.004 0.833 View mutations
57 V 19 0 19 0.007 0.896 View mutations
58 D 19 0 19 0.002 0.907 View mutations
59 T 19 0 19 0.003 0.968 View mutations
60 S 19 0 19 0.012 1.000 View mutations
61 Q 19 0 19 0.011 0.996 View mutations
62 V 19 0 19 0.030 0.957 View mutations
63 L 19 0 19 0.004 0.942 View mutations
64 Y 19 0 19 0.003 0.942 View mutations
65 E 19 0 19 0.000 0.905 View mutations
66 W 19 0 19 0.001 0.912 View mutations
67 E 19 0 19 0.003 0.914 View mutations
68 Q 19 0 19 0.002 0.947 View mutations
69 G 19 0 19 0.000 0.938 View mutations
70 F 19 0 19 0.000 0.935 View mutations
71 S 19 0 19 0.003 0.964 View mutations
72 Q 19 0 19 0.006 0.919 View mutations
73 S 19 0 19 0.013 0.926 View mutations
74 F 19 0 19 0.009 0.922 View mutations
75 T 19 0 19 0.017 0.889 View mutations