P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 Q 19 0 19 0.006 0.687 View mutations
27 Q 19 0 19 0.012 0.705 View mutations
28 Q 19 0 19 0.020 0.823 View mutations
29 S 18 1 19 0.081 0.714 View mutations
30 Y 19 0 19 0.081 0.642 View mutations
31 L 19 0 19 0.006 0.668 View mutations
32 D 4 15 19 0.702 0.429 View mutations
33 S 0 19 19 0.997 0.387 View mutations
34 G 2 17 19 0.909 0.448 View mutations
35 I 5 14 19 0.727 0.422 View mutations
36 H 19 0 19 0.004 0.553 View mutations
37 S 18 1 19 0.115 0.646 View mutations
38 G 6 13 19 0.631 0.403 View mutations
39 A 11 8 19 0.505 0.500 View mutations
40 T 18 1 19 0.064 0.774 View mutations
41 T 3 16 19 0.756 0.257 View mutations
42 T 18 1 19 0.073 0.704 View mutations
43 A 19 0 19 0.000 0.733 View mutations
44 P 19 0 19 0.049 0.725 View mutations
45 S 5 14 19 0.744 0.325 View mutations
46 L 17 2 19 0.121 0.713 View mutations
47 S 19 0 19 0.007 0.879 View mutations
48 G 18 1 19 0.033 0.778 View mutations
49 K 19 0 19 0.018 0.903 View mutations
50 G 18 1 19 0.109 0.925 View mutations