P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
751 D 19 0 19 0.007 0.827 View mutations
752 G 19 0 19 0.000 0.868 View mutations
753 L 19 0 19 0.000 0.850 View mutations
754 P 19 0 19 0.001 0.835 View mutations
755 D 19 0 19 0.032 0.802 View mutations
756 L 19 0 19 0.003 0.827 View mutations
757 G 19 0 19 0.001 0.810 View mutations
758 H 19 0 19 0.000 0.835 View mutations
759 A 19 0 19 0.000 0.833 View mutations
760 Q 19 0 19 0.000 0.846 View mutations
761 D 19 0 19 0.000 0.820 View mutations
762 L 19 0 19 0.000 0.768 View mutations
763 M 19 0 19 0.000 0.854 View mutations
764 D 19 0 19 0.000 0.795 View mutations
765 G 19 0 19 0.000 0.740 View mutations
766 L 19 0 19 0.000 0.758 View mutations
767 P 19 0 19 0.003 0.686 View mutations
768 P 19 0 19 0.010 0.622 View mutations
769 G 19 0 19 0.004 0.654 View mutations
770 D 11 8 19 0.409 0.495 View mutations
771 S 17 2 19 0.124 0.667 View mutations
772 N 18 1 19 0.053 0.657 View mutations
773 Q 9 10 19 0.520 0.448 View mutations
774 L 10 9 19 0.517 0.473 View mutations
775 A 6 13 19 0.679 0.411 View mutations