P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
726 Q 19 0 19 0.003 0.928 View mutations
727 D 19 0 19 0.000 0.895 View mutations
728 A 19 0 19 0.000 0.931 View mutations
729 L 19 0 19 0.026 0.960 View mutations
730 G 18 1 19 0.058 0.834 View mutations
731 M 19 0 19 0.001 0.915 View mutations
732 D 19 0 19 0.028 0.874 View mutations
733 P 19 0 19 0.041 0.875 View mutations
734 M 16 3 19 0.187 0.781 View mutations
735 M 18 1 19 0.068 0.821 View mutations
736 E 19 0 19 0.007 0.887 View mutations
737 H 19 0 19 0.048 0.836 View mutations
738 E 19 0 19 0.006 0.867 View mutations
739 M 19 0 19 0.000 0.857 View mutations
740 G 8 11 19 0.574 0.424 View mutations
741 G 19 0 19 0.007 0.894 View mutations
742 H 18 1 19 0.061 0.890 View mutations
743 H 19 0 19 0.011 0.944 View mutations
744 P 19 0 19 0.001 0.903 View mutations
745 G 17 2 19 0.115 0.813 View mutations
746 A 19 0 19 0.003 0.947 View mutations
747 D 17 2 19 0.119 0.764 View mutations
748 Y 19 0 19 0.000 0.819 View mutations
749 P 19 0 19 0.007 0.892 View mutations
750 V 19 0 19 0.001 0.926 View mutations