P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 S 19 0 19 0.067 0.874 View mutations
252 H 18 1 19 0.081 0.856 View mutations
253 P 18 1 19 0.077 0.846 View mutations
254 K 16 3 19 0.166 0.747 View mutations
255 P 7 12 19 0.616 0.390 View mutations
256 S 6 13 19 0.711 0.354 View mutations
257 S 2 17 19 0.844 0.232 View mutations
258 P 4 15 19 0.751 0.312 View mutations
259 R 16 3 19 0.194 0.692 View mutations
260 Q 17 2 19 0.103 0.757 View mutations
261 E 6 13 19 0.652 0.376 View mutations
262 S 9 10 19 0.509 0.460 View mutations
263 T 15 4 19 0.219 0.580 View mutations
264 R 17 2 19 0.109 0.541 View mutations
265 V 12 7 19 0.341 0.476 View mutations
266 I 19 0 19 0.013 0.554 View mutations
267 Q 2 17 19 0.806 0.391 View mutations
268 L 11 8 19 0.401 0.474 View mutations
269 M 5 14 19 0.704 0.385 View mutations
270 P 14 5 19 0.365 0.470 View mutations
271 S 9 10 19 0.521 0.447 View mutations
272 P 15 4 19 0.219 0.515 View mutations
273 I 16 3 19 0.162 0.564 View mutations
274 M 9 10 19 0.518 0.446 View mutations
275 H 7 12 19 0.541 0.413 View mutations