P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 G 16 3 19 0.123 0.739 View mutations
302 K 10 9 19 0.498 0.507 View mutations
303 P 11 8 19 0.421 0.535 View mutations
304 I 13 6 19 0.328 0.635 View mutations
305 N 9 10 19 0.518 0.464 View mutations
306 L 19 0 19 0.029 0.796 View mutations
307 S 18 1 19 0.035 0.777 View mutations
308 H 18 1 19 0.030 0.772 View mutations
309 R 19 0 19 0.032 0.751 View mutations
310 E 19 0 19 0.023 0.704 View mutations
311 D 18 1 19 0.099 0.591 View mutations
312 L 19 0 19 0.005 0.714 View mutations
313 A 19 0 19 0.003 0.683 View mutations
314 Y 11 8 19 0.376 0.478 View mutations
315 M 14 5 19 0.259 0.528 View mutations
316 N 15 4 19 0.236 0.562 View mutations
317 H 12 7 19 0.330 0.494 View mutations
318 I 19 0 19 0.026 0.606 View mutations
319 M 14 5 19 0.256 0.558 View mutations
320 V 17 2 19 0.148 0.585 View mutations
321 S 17 2 19 0.120 0.583 View mutations
322 V 9 10 19 0.573 0.443 View mutations
323 S 9 10 19 0.468 0.445 View mutations
324 P 4 15 19 0.714 0.406 View mutations
325 P 8 11 19 0.553 0.433 View mutations