P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 E 10 9 19 0.535 0.443 View mutations
327 E 18 1 19 0.129 0.497 View mutations
328 H 14 5 19 0.279 0.531 View mutations
329 A 14 5 19 0.273 0.535 View mutations
330 M 4 15 19 0.742 0.399 View mutations
331 P 0 19 19 1.000 0.554 View mutations
332 I 2 17 19 0.884 0.513 View mutations
333 G 4 15 19 0.757 0.596 View mutations
334 R 0 19 19 1.000 0.616 View mutations
335 I 6 13 19 0.631 0.544 View mutations
336 A 9 10 19 0.577 0.509 View mutations
337 D 5 14 19 0.758 0.614 View mutations
338 C 1 18 19 0.911 0.648 View mutations
339 R 1 18 19 0.950 0.693 View mutations
340 L 0 19 19 0.998 0.723 View mutations
341 L 1 18 19 0.944 0.672 View mutations
342 W 0 19 19 1.000 0.655 View mutations
343 D 0 19 19 1.000 0.789 View mutations
344 Y 0 19 19 1.000 0.748 View mutations
345 V 0 19 19 0.998 0.654 View mutations
346 Y 0 19 19 0.996 0.786 View mutations
347 Q 0 19 19 1.000 0.782 View mutations
348 L 0 19 19 1.000 0.887 View mutations
349 L 0 19 19 1.000 0.826 View mutations
350 S 0 19 19 0.994 0.786 View mutations