P41212 (P41212)

Overview
Predicted structure (AF):
AF-P41212-F1-model_v4
Uniprot entry:
P41212
Gene:
P41212
Protein length:
452 residues
Mutations found:
8587
Benign based on D2Deep prediction:
4526 out of 8587 mutations
Pathogenic based on D2Deep prediction:
4061 out of 8587 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8587 mutations across 452 unique positions. There are 4526 benign and 4061 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 D 0 19 19 1.000 0.836 View mutations
352 S 2 17 19 0.884 0.657 View mutations
353 R 0 19 19 1.000 0.810 View mutations
354 Y 0 19 19 1.000 0.817 View mutations
355 E 1 18 19 0.947 0.692 View mutations
356 N 9 10 19 0.552 0.510 View mutations
357 F 1 18 19 0.947 0.744 View mutations
358 I 0 19 19 1.000 0.836 View mutations
359 R 0 19 19 1.000 0.760 View mutations
360 W 0 19 19 1.000 0.680 View mutations
361 E 0 19 19 0.989 0.740 View mutations
362 D 1 18 19 0.961 0.590 View mutations
363 K 4 15 19 0.782 0.514 View mutations
364 E 2 17 19 0.906 0.549 View mutations
365 S 5 14 19 0.756 0.531 View mutations
366 K 1 18 19 0.923 0.624 View mutations
367 I 1 18 19 0.961 0.681 View mutations
368 F 0 19 19 0.999 0.765 View mutations
369 R 0 19 19 0.998 0.812 View mutations
370 I 3 16 19 0.853 0.739 View mutations
371 V 8 11 19 0.528 0.535 View mutations
372 D 2 17 19 0.880 0.818 View mutations
373 P 0 19 19 1.000 0.939 View mutations
374 N 0 19 19 1.000 0.859 View mutations
375 G 0 19 19 0.998 0.859 View mutations