P42771 (CDKN2A)

Overview
Predicted structure (AF):
AF-P42771-F1-model_v4
Uniprot entry:
P42771
Gene:
CDKN2A
Protein length:
156 residues
Mutations found:
2963
Benign based on D2Deep prediction:
1926 out of 2963 mutations
Pathogenic based on D2Deep prediction:
1037 out of 2963 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2963 mutations across 156 unique positions. There are 1926 benign and 1037 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 18 0 18 0.023 0.681 View mutations
2 E 19 0 19 0.007 0.819 View mutations
3 P 15 4 19 0.209 0.686 View mutations
4 A 19 0 19 0.001 0.863 View mutations
5 A 19 0 19 0.009 0.823 View mutations
6 G 16 3 19 0.145 0.727 View mutations
7 S 18 1 19 0.045 0.864 View mutations
8 S 18 1 19 0.059 0.900 View mutations
9 M 19 0 19 0.010 0.991 View mutations
10 E 19 0 19 0.004 0.907 View mutations
11 P 19 0 19 0.053 0.949 View mutations
12 S 18 1 19 0.097 0.947 View mutations
13 A 19 0 19 0.048 0.866 View mutations
14 D 17 2 19 0.181 0.663 View mutations
15 W 19 0 19 0.041 0.852 View mutations
16 L 15 4 19 0.180 0.497 View mutations
17 A 14 5 19 0.282 0.447 View mutations
18 T 18 1 19 0.108 0.616 View mutations
19 A 18 1 19 0.130 0.402 View mutations
20 A 4 15 19 0.759 0.593 View mutations
21 A 3 16 19 0.819 0.611 View mutations
22 R 18 1 19 0.055 0.478 View mutations
23 G 7 12 19 0.629 0.506 View mutations
24 R 8 11 19 0.520 0.432 View mutations
25 V 8 11 19 0.549 0.432 View mutations