P42771 (CDKN2A)

Overview
Predicted structure (AF):
AF-P42771-F1-model_v4
Uniprot entry:
P42771
Gene:
CDKN2A
Protein length:
156 residues
Mutations found:
2963
Benign based on D2Deep prediction:
1926 out of 2963 mutations
Pathogenic based on D2Deep prediction:
1037 out of 2963 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2963 mutations across 156 unique positions. There are 1926 benign and 1037 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 E 15 4 19 0.227 0.580 View mutations
27 E 19 0 19 0.007 0.652 View mutations
28 V 17 2 19 0.204 0.450 View mutations
29 R 5 14 19 0.736 0.400 View mutations
30 A 19 0 19 0.030 0.594 View mutations
31 L 19 0 19 0.082 0.464 View mutations
32 L 8 11 19 0.597 0.515 View mutations
33 E 17 2 19 0.174 0.506 View mutations
34 A 19 0 19 0.023 0.555 View mutations
35 G 11 8 19 0.438 0.431 View mutations
36 A 19 0 19 0.020 0.532 View mutations
37 L 19 0 19 0.001 0.487 View mutations
38 P 5 14 19 0.702 0.460 View mutations
39 N 5 14 19 0.693 0.440 View mutations
40 A 15 4 19 0.190 0.446 View mutations
41 P 12 7 19 0.436 0.412 View mutations
42 N 8 11 19 0.562 0.436 View mutations
43 S 19 0 19 0.003 0.512 View mutations
44 Y 10 9 19 0.363 0.433 View mutations
45 G 0 19 19 0.998 0.686 View mutations
46 R 0 19 19 0.999 0.561 View mutations
47 R 2 17 19 0.800 0.480 View mutations
48 P 1 18 19 0.956 0.637 View mutations
49 I 6 13 19 0.720 0.546 View mutations
50 Q 0 19 19 1.000 0.692 View mutations