P42771 (CDKN2A)

Overview
Predicted structure (AF):
AF-P42771-F1-model_v4
Uniprot entry:
P42771
Gene:
CDKN2A
Protein length:
156 residues
Mutations found:
2963
Benign based on D2Deep prediction:
1926 out of 2963 mutations
Pathogenic based on D2Deep prediction:
1037 out of 2963 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2963 mutations across 156 unique positions. There are 1926 benign and 1037 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 V 0 19 19 1.000 0.733 View mutations
52 M 1 18 19 0.926 0.610 View mutations
53 M 1 18 19 0.931 0.634 View mutations
54 M 16 3 19 0.205 0.326 View mutations
55 G 19 0 19 0.002 0.312 View mutations
56 S 19 0 19 0.034 0.473 View mutations
57 A 10 9 19 0.456 0.421 View mutations
58 R 19 0 19 0.086 0.582 View mutations
59 V 7 12 19 0.652 0.521 View mutations
60 A 12 7 19 0.397 0.427 View mutations
61 E 2 17 19 0.831 0.462 View mutations
62 L 1 18 19 0.943 0.459 View mutations
63 L 18 1 19 0.057 0.272 View mutations
64 L 15 4 19 0.318 0.369 View mutations
65 L 18 1 19 0.073 0.398 View mutations
66 H 10 9 19 0.399 0.426 View mutations
67 G 0 19 19 0.988 0.902 View mutations
68 A 15 4 19 0.251 0.297 View mutations
69 E 18 1 19 0.060 0.350 View mutations
70 P 4 15 19 0.784 0.658 View mutations
71 N 1 18 19 0.907 0.665 View mutations
72 C 10 9 19 0.507 0.498 View mutations
73 A 2 17 19 0.880 0.600 View mutations
74 D 0 19 19 0.999 0.591 View mutations
75 P 8 11 19 0.564 0.519 View mutations