P42771 (CDKN2A)

Overview
Predicted structure (AF):
AF-P42771-F1-model_v4
Uniprot entry:
P42771
Gene:
CDKN2A
Protein length:
156 residues
Mutations found:
2963
Benign based on D2Deep prediction:
1926 out of 2963 mutations
Pathogenic based on D2Deep prediction:
1037 out of 2963 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2963 mutations across 156 unique positions. There are 1926 benign and 1037 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 A 16 3 19 0.196 0.499 View mutations
77 T 3 16 19 0.789 0.655 View mutations
78 L 0 19 19 0.997 0.615 View mutations
79 T 0 19 19 0.995 0.706 View mutations
80 R 0 19 19 1.000 0.534 View mutations
81 P 0 19 19 1.000 0.800 View mutations
82 V 0 19 19 0.999 0.755 View mutations
83 H 0 19 19 1.000 0.798 View mutations
84 D 0 19 19 0.999 0.704 View mutations
85 A 12 7 19 0.412 0.382 View mutations
86 A 3 16 19 0.842 0.842 View mutations
87 R 14 5 19 0.410 0.352 View mutations
88 E 18 1 19 0.051 0.189 View mutations
89 G 2 17 19 0.857 0.838 View mutations
90 F 17 2 19 0.118 0.262 View mutations
91 L 19 0 19 0.002 0.410 View mutations
92 D 19 0 19 0.024 0.400 View mutations
93 T 19 0 19 0.042 0.286 View mutations
94 L 16 3 19 0.162 0.375 View mutations
95 V 13 6 19 0.263 0.417 View mutations
96 V 11 8 19 0.399 0.421 View mutations
97 L 18 1 19 0.041 0.216 View mutations
98 H 18 1 19 0.126 0.369 View mutations
99 R 15 4 19 0.258 0.403 View mutations
100 A 13 6 19 0.304 0.450 View mutations