P42771 (CDKN2A)

Overview
Predicted structure (AF):
AF-P42771-F1-model_v4
Uniprot entry:
P42771
Gene:
CDKN2A
Protein length:
156 residues
Mutations found:
2963
Benign based on D2Deep prediction:
1926 out of 2963 mutations
Pathogenic based on D2Deep prediction:
1037 out of 2963 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2963 mutations across 156 unique positions. There are 1926 benign and 1037 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 V 16 3 19 0.223 0.404 View mutations
127 A 9 10 19 0.536 0.444 View mutations
128 R 15 4 19 0.250 0.522 View mutations
129 Y 18 1 19 0.095 0.498 View mutations
130 L 0 19 19 0.979 0.519 View mutations
131 R 14 5 19 0.378 0.531 View mutations
132 A 18 1 19 0.127 0.658 View mutations
133 A 15 4 19 0.253 0.572 View mutations
134 A 7 12 19 0.655 0.400 View mutations
135 G 19 0 19 0.031 0.719 View mutations
136 G 19 0 19 0.042 0.723 View mutations
137 T 17 2 19 0.117 0.730 View mutations
138 R 19 0 19 0.037 0.784 View mutations
139 G 17 2 19 0.100 0.712 View mutations
140 S 19 0 19 0.014 0.780 View mutations
141 N 19 0 19 0.005 0.843 View mutations
142 H 19 0 19 0.018 0.852 View mutations
143 A 19 0 19 0.004 0.856 View mutations
144 R 19 0 19 0.021 0.858 View mutations
145 I 19 0 19 0.071 0.830 View mutations
146 D 19 0 19 0.003 0.874 View mutations
147 A 17 2 19 0.081 0.713 View mutations
148 A 19 0 19 0.000 0.681 View mutations
149 E 19 0 19 0.000 0.672 View mutations
150 G 19 0 19 0.001 0.779 View mutations