P42771 (CDKN2A)

Overview
Predicted structure (AF):
AF-P42771-F1-model_v4
Uniprot entry:
P42771
Gene:
CDKN2A
Protein length:
156 residues
Mutations found:
2963
Benign based on D2Deep prediction:
1926 out of 2963 mutations
Pathogenic based on D2Deep prediction:
1037 out of 2963 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2963 mutations across 156 unique positions. There are 1926 benign and 1037 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 G 19 0 19 0.000 0.106 View mutations
102 A 19 0 19 0.002 0.032 View mutations
103 R 3 16 19 0.777 0.536 View mutations
104 L 0 19 19 0.990 0.800 View mutations
105 D 0 19 19 1.000 0.688 View mutations
106 V 8 11 19 0.501 0.537 View mutations
107 R 19 0 19 0.011 0.434 View mutations
108 D 1 18 19 0.942 0.752 View mutations
109 A 19 0 19 0.001 0.417 View mutations
110 W 18 1 19 0.130 0.387 View mutations
111 G 17 2 19 0.148 0.227 View mutations
112 R 0 19 19 0.980 0.806 View mutations
113 L 18 1 19 0.051 0.393 View mutations
114 P 2 17 19 0.872 0.726 View mutations
115 V 9 10 19 0.551 0.430 View mutations
116 D 19 0 19 0.041 0.391 View mutations
117 L 1 18 19 0.929 0.776 View mutations
118 A 6 13 19 0.650 0.579 View mutations
119 E 19 0 19 0.074 0.369 View mutations
120 E 14 5 19 0.284 0.448 View mutations
121 L 16 3 19 0.182 0.479 View mutations
122 G 19 0 19 0.011 0.465 View mutations
123 H 0 19 19 0.983 0.506 View mutations
124 R 19 0 19 0.004 0.605 View mutations
125 D 19 0 19 0.039 0.521 View mutations