P42772 (CDKN2B)

Overview
Predicted structure (AF):
AF-P42772-F1-model_v4
Uniprot entry:
P42772
Gene:
CDKN2B
Protein length:
138 residues
Mutations found:
2621
Benign based on D2Deep prediction:
1462 out of 2621 mutations
Pathogenic based on D2Deep prediction:
1159 out of 2621 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2621 mutations across 138 unique positions. There are 1462 benign and 1159 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 R 19 0 19 0.002 0.737 View mutations
127 D 16 3 19 0.168 0.617 View mutations
128 V 1 18 19 0.945 0.390 View mutations
129 A 16 3 19 0.153 0.636 View mutations
130 G 18 1 19 0.056 0.705 View mutations
131 Y 2 17 19 0.894 0.311 View mutations
132 L 0 19 19 0.979 0.395 View mutations
133 R 15 4 19 0.238 0.642 View mutations
134 T 18 1 19 0.044 0.725 View mutations
135 A 16 3 19 0.165 0.682 View mutations
136 T 18 1 19 0.045 0.708 View mutations
137 G 16 3 19 0.214 0.620 View mutations
138 D 19 0 19 0.015 0.653 View mutations