P42772 (CDKN2B)

Overview
Predicted structure (AF):
AF-P42772-F1-model_v4
Uniprot entry:
P42772
Gene:
CDKN2B
Protein length:
138 residues
Mutations found:
2621
Benign based on D2Deep prediction:
1462 out of 2621 mutations
Pathogenic based on D2Deep prediction:
1159 out of 2621 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2621 mutations across 138 unique positions. There are 1462 benign and 1159 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 17 1 18 0.096 0.589 View mutations
2 R 18 1 19 0.062 0.822 View mutations
3 E 12 7 19 0.466 0.567 View mutations
4 E 18 1 19 0.076 0.835 View mutations
5 N 19 0 19 0.009 0.907 View mutations
6 K 17 2 19 0.129 0.768 View mutations
7 G 19 0 19 0.000 0.836 View mutations
8 M 16 3 19 0.179 0.803 View mutations
9 P 19 0 19 0.002 0.860 View mutations
10 S 19 0 19 0.000 0.881 View mutations
11 G 19 0 19 0.002 0.855 View mutations
12 G 19 0 19 0.021 0.892 View mutations
13 G 19 0 19 0.011 0.877 View mutations
14 S 12 7 19 0.337 0.632 View mutations
15 D 17 2 19 0.158 0.858 View mutations
16 E 19 0 19 0.063 0.951 View mutations
17 G 12 7 19 0.440 0.630 View mutations
18 L 1 18 19 0.937 0.300 View mutations
19 A 15 4 19 0.230 0.551 View mutations
20 S 17 2 19 0.144 0.678 View mutations
21 A 1 18 19 0.926 0.405 View mutations
22 A 8 11 19 0.545 0.519 View mutations
23 A 14 5 19 0.296 0.439 View mutations
24 R 13 6 19 0.337 0.472 View mutations
25 G 2 17 19 0.887 0.534 View mutations