P42772 (CDKN2B)

Overview
Predicted structure (AF):
AF-P42772-F1-model_v4
Uniprot entry:
P42772
Gene:
CDKN2B
Protein length:
138 residues
Mutations found:
2621
Benign based on D2Deep prediction:
1462 out of 2621 mutations
Pathogenic based on D2Deep prediction:
1159 out of 2621 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2621 mutations across 138 unique positions. There are 1462 benign and 1159 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 R 19 0 19 0.001 0.399 View mutations
102 A 0 19 19 0.959 0.591 View mutations
103 G 0 19 19 1.000 0.924 View mutations
104 A 0 19 19 1.000 0.986 View mutations
105 R 2 17 19 0.868 0.478 View mutations
106 L 3 16 19 0.851 0.636 View mutations
107 D 15 4 19 0.268 0.436 View mutations
108 V 4 15 19 0.815 0.569 View mutations
109 R 19 0 19 0.001 0.481 View mutations
110 D 11 8 19 0.440 0.468 View mutations
111 A 19 0 19 0.033 0.474 View mutations
112 W 19 0 19 0.020 0.444 View mutations
113 G 19 0 19 0.021 0.188 View mutations
114 R 18 1 19 0.066 0.316 View mutations
115 L 10 9 19 0.476 0.421 View mutations
116 P 2 17 19 0.912 0.659 View mutations
117 V 11 8 19 0.427 0.443 View mutations
118 D 18 1 19 0.086 0.454 View mutations
119 L 5 14 19 0.599 0.610 View mutations
120 A 7 12 19 0.638 0.523 View mutations
121 E 17 2 19 0.155 0.557 View mutations
122 E 14 5 19 0.313 0.416 View mutations
123 R 19 0 19 0.059 0.542 View mutations
124 G 8 11 19 0.549 0.433 View mutations
125 H 4 15 19 0.815 0.406 View mutations