P42772 (CDKN2B)

Overview
Predicted structure (AF):
AF-P42772-F1-model_v4
Uniprot entry:
P42772
Gene:
CDKN2B
Protein length:
138 residues
Mutations found:
2621
Benign based on D2Deep prediction:
1462 out of 2621 mutations
Pathogenic based on D2Deep prediction:
1159 out of 2621 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 2621 mutations across 138 unique positions. There are 1462 benign and 1159 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 D 1 18 19 0.940 0.573 View mutations
77 P 19 0 19 0.004 0.335 View mutations
78 A 15 4 19 0.213 0.413 View mutations
79 T 8 11 19 0.548 0.538 View mutations
80 L 6 13 19 0.687 0.541 View mutations
81 T 6 13 19 0.691 0.543 View mutations
82 R 0 19 19 0.980 0.424 View mutations
83 P 0 19 19 0.998 0.801 View mutations
84 V 5 14 19 0.643 0.632 View mutations
85 H 0 19 19 0.999 0.752 View mutations
86 D 0 19 19 0.967 0.662 View mutations
87 A 0 19 19 0.957 0.968 View mutations
88 A 0 19 19 0.999 1.000 View mutations
89 R 18 1 19 0.084 0.226 View mutations
90 E 19 0 19 0.011 0.138 View mutations
91 G 7 12 19 0.608 0.610 View mutations
92 F 19 0 19 0.002 0.138 View mutations
93 L 5 14 19 0.759 0.537 View mutations
94 D 19 0 19 0.001 0.395 View mutations
95 T 11 8 19 0.407 0.463 View mutations
96 L 0 19 19 0.981 0.688 View mutations
97 V 19 0 19 0.049 0.526 View mutations
98 V 17 2 19 0.148 0.465 View mutations
99 L 3 16 19 0.846 0.743 View mutations
100 H 4 15 19 0.791 0.567 View mutations