P42773 (CDKN2C)

Overview
Predicted structure (AF):
AF-P42773-F1-model_v4
Uniprot entry:
P42773
Gene:
CDKN2C
Protein length:
168 residues
Mutations found:
3191
Benign based on D2Deep prediction:
1762 out of 3191 mutations
Pathogenic based on D2Deep prediction:
1429 out of 3191 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3191 mutations across 168 unique positions. There are 1762 benign and 1429 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
1 M 0 18 18 0.884 0.477 View mutations
2 A 14 5 19 0.295 0.444 View mutations
3 E 3 16 19 0.821 0.405 View mutations
4 P 10 9 19 0.449 0.446 View mutations
5 W 6 13 19 0.627 0.361 View mutations
6 G 12 7 19 0.390 0.458 View mutations
7 N 19 0 19 0.000 0.531 View mutations
8 E 19 0 19 0.098 0.492 View mutations
9 L 4 15 19 0.742 0.535 View mutations
10 A 18 1 19 0.081 0.447 View mutations
11 S 18 1 19 0.034 0.383 View mutations
12 A 13 6 19 0.299 0.428 View mutations
13 A 8 11 19 0.591 0.553 View mutations
14 A 15 4 19 0.278 0.291 View mutations
15 R 17 2 19 0.158 0.409 View mutations
16 G 10 9 19 0.389 0.489 View mutations
17 D 19 0 19 0.060 0.500 View mutations
18 L 8 11 19 0.523 0.434 View mutations
19 E 18 1 19 0.210 0.586 View mutations
20 Q 6 13 19 0.614 0.399 View mutations
21 L 1 18 19 0.945 0.464 View mutations
22 T 15 4 19 0.225 0.601 View mutations
23 S 11 8 19 0.389 0.479 View mutations
24 L 0 19 19 0.999 0.358 View mutations
25 L 4 15 19 0.818 0.424 View mutations