P42773 (CDKN2C)

Overview
Predicted structure (AF):
AF-P42773-F1-model_v4
Uniprot entry:
P42773
Gene:
CDKN2C
Protein length:
168 residues
Mutations found:
3191
Benign based on D2Deep prediction:
1762 out of 3191 mutations
Pathogenic based on D2Deep prediction:
1429 out of 3191 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3191 mutations across 168 unique positions. There are 1762 benign and 1429 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 Q 14 5 19 0.214 0.575 View mutations
27 N 6 13 19 0.680 0.377 View mutations
28 N 6 13 19 0.633 0.370 View mutations
29 V 2 17 19 0.839 0.396 View mutations
30 N 1 18 19 0.796 0.343 View mutations
31 V 8 11 19 0.531 0.515 View mutations
32 N 1 18 19 0.869 0.547 View mutations
33 A 7 12 19 0.591 0.509 View mutations
34 Q 11 8 19 0.481 0.432 View mutations
35 N 1 18 19 0.930 0.618 View mutations
36 G 19 0 19 0.070 0.427 View mutations
37 F 6 13 19 0.672 0.573 View mutations
38 G 0 19 19 0.952 0.771 View mutations
39 R 0 19 19 0.993 0.746 View mutations
40 T 0 19 19 0.982 0.900 View mutations
41 A 0 19 19 0.978 0.863 View mutations
42 L 2 17 19 0.901 0.708 View mutations
43 Q 7 12 19 0.597 0.542 View mutations
44 V 1 18 19 0.957 0.622 View mutations
45 M 0 19 19 0.962 0.523 View mutations
46 K 3 16 19 0.818 0.546 View mutations
47 L 9 10 19 0.497 0.510 View mutations
48 G 1 18 19 0.946 0.692 View mutations
49 N 2 17 19 0.830 0.525 View mutations
50 P 0 19 19 1.000 0.658 View mutations