P42773 (CDKN2C)

Overview
Predicted structure (AF):
AF-P42773-F1-model_v4
Uniprot entry:
P42773
Gene:
CDKN2C
Protein length:
168 residues
Mutations found:
3191
Benign based on D2Deep prediction:
1762 out of 3191 mutations
Pathogenic based on D2Deep prediction:
1429 out of 3191 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3191 mutations across 168 unique positions. There are 1762 benign and 1429 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 E 19 0 19 0.088 0.740 View mutations
152 V 1 18 19 0.950 0.284 View mutations
153 V 19 0 19 0.009 0.766 View mutations
154 S 19 0 19 0.000 0.713 View mutations
155 L 18 1 19 0.098 0.862 View mutations
156 M 16 3 19 0.121 0.682 View mutations
157 Q 19 0 19 0.001 0.848 View mutations
158 A 19 0 19 0.001 0.821 View mutations
159 N 19 0 19 0.040 0.956 View mutations
160 G 19 0 19 0.004 1.000 View mutations
161 A 19 0 19 0.007 0.904 View mutations
162 G 19 0 19 0.039 0.883 View mutations
163 G 15 4 19 0.232 0.647 View mutations
164 A 16 3 19 0.161 0.676 View mutations
165 T 19 0 19 0.011 0.819 View mutations
166 N 19 0 19 0.006 0.838 View mutations
167 L 19 0 19 0.005 0.710 View mutations
168 Q 19 0 19 0.006 0.694 View mutations