P42773 (CDKN2C)

Overview
Predicted structure (AF):
AF-P42773-F1-model_v4
Uniprot entry:
P42773
Gene:
CDKN2C
Protein length:
168 residues
Mutations found:
3191
Benign based on D2Deep prediction:
1762 out of 3191 mutations
Pathogenic based on D2Deep prediction:
1429 out of 3191 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3191 mutations across 168 unique positions. There are 1762 benign and 1429 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 E 8 11 19 0.615 0.432 View mutations
52 I 2 17 19 0.856 0.506 View mutations
53 A 0 19 19 0.999 0.801 View mutations
54 R 1 18 19 0.867 0.474 View mutations
55 R 19 0 19 0.056 0.679 View mutations
56 L 10 9 19 0.521 0.497 View mutations
57 L 1 18 19 0.870 0.669 View mutations
58 L 18 1 19 0.041 0.538 View mutations
59 R 18 1 19 0.069 0.622 View mutations
60 G 0 19 19 0.976 0.752 View mutations
61 A 1 18 19 0.920 0.904 View mutations
62 N 5 14 19 0.644 0.541 View mutations
63 P 5 14 19 0.733 0.634 View mutations
64 D 17 2 19 0.212 0.342 View mutations
65 L 13 6 19 0.379 0.428 View mutations
66 K 18 1 19 0.186 0.436 View mutations
67 D 1 18 19 0.939 0.762 View mutations
68 R 16 3 19 0.148 0.423 View mutations
69 T 19 0 19 0.005 0.339 View mutations
70 G 12 7 19 0.439 0.437 View mutations
71 F 1 18 19 0.914 0.784 View mutations
72 A 4 15 19 0.780 0.599 View mutations
73 V 1 18 19 0.929 0.696 View mutations
74 I 3 16 19 0.856 0.653 View mutations
75 H 1 18 19 0.956 0.790 View mutations