P42773 (CDKN2C)

Overview
Predicted structure (AF):
AF-P42773-F1-model_v4
Uniprot entry:
P42773
Gene:
CDKN2C
Protein length:
168 residues
Mutations found:
3191
Benign based on D2Deep prediction:
1762 out of 3191 mutations
Pathogenic based on D2Deep prediction:
1429 out of 3191 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3191 mutations across 168 unique positions. There are 1762 benign and 1429 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 T 7 12 19 0.585 0.386 View mutations
127 A 6 13 19 0.656 0.368 View mutations
128 S 1 18 19 0.923 0.306 View mutations
129 N 9 10 19 0.550 0.452 View mutations
130 V 14 5 19 0.349 0.488 View mutations
131 G 6 13 19 0.690 0.395 View mutations
132 H 0 19 19 0.992 0.504 View mutations
133 R 8 11 19 0.543 0.435 View mutations
134 N 0 19 19 0.962 0.576 View mutations
135 H 19 0 19 0.029 0.411 View mutations
136 K 19 0 19 0.009 0.476 View mutations
137 G 19 0 19 0.073 0.248 View mutations
138 D 18 1 19 0.100 0.481 View mutations
139 T 17 2 19 0.132 0.387 View mutations
140 A 19 0 19 0.009 0.398 View mutations
141 C 19 0 19 0.007 0.678 View mutations
142 D 19 0 19 0.040 0.477 View mutations
143 L 18 1 19 0.139 0.399 View mutations
144 A 11 8 19 0.364 0.473 View mutations
145 R 19 0 19 0.001 0.564 View mutations
146 L 19 0 19 0.001 0.369 View mutations
147 Y 18 1 19 0.093 0.448 View mutations
148 G 19 0 19 0.001 0.571 View mutations
149 R 14 5 19 0.308 0.460 View mutations
150 N 19 0 19 0.000 0.724 View mutations