P42773 (CDKN2C)

Overview
Predicted structure (AF):
AF-P42773-F1-model_v4
Uniprot entry:
P42773
Gene:
CDKN2C
Protein length:
168 residues
Mutations found:
3191
Benign based on D2Deep prediction:
1762 out of 3191 mutations
Pathogenic based on D2Deep prediction:
1429 out of 3191 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3191 mutations across 168 unique positions. There are 1762 benign and 1429 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 N 19 0 19 0.019 0.431 View mutations
102 E 19 0 19 0.023 0.341 View mutations
103 G 13 6 19 0.389 0.356 View mutations
104 N 0 19 19 0.969 0.849 View mutations
105 L 1 18 19 0.911 0.575 View mutations
106 P 4 15 19 0.735 0.701 View mutations
107 L 13 6 19 0.300 0.340 View mutations
108 H 2 17 19 0.830 0.725 View mutations
109 L 15 4 19 0.200 0.382 View mutations
110 A 11 8 19 0.366 0.429 View mutations
111 A 8 11 19 0.643 0.556 View mutations
112 K 19 0 19 0.073 0.446 View mutations
113 E 19 0 19 0.026 0.230 View mutations
114 G 19 0 19 0.024 0.196 View mutations
115 H 18 1 19 0.193 0.412 View mutations
116 L 13 6 19 0.330 0.496 View mutations
117 R 19 0 19 0.046 0.659 View mutations
118 V 9 10 19 0.523 0.430 View mutations
119 V 13 6 19 0.308 0.419 View mutations
120 E 18 1 19 0.157 0.709 View mutations
121 F 6 13 19 0.674 0.350 View mutations
122 L 13 6 19 0.279 0.449 View mutations
123 V 19 0 19 0.013 0.642 View mutations
124 K 19 0 19 0.000 0.790 View mutations
125 H 18 1 19 0.099 0.889 View mutations