P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 E 0 19 19 1.000 0.738 View mutations
277 G 0 19 19 1.000 0.714 View mutations
278 E 2 17 19 0.897 0.608 View mutations
279 V 1 18 19 0.933 0.569 View mutations
280 N 1 18 19 0.954 0.544 View mutations
281 G 0 19 19 1.000 0.637 View mutations
282 R 1 18 19 0.937 0.548 View mutations
283 K 2 17 19 0.878 0.447 View mutations
284 G 0 19 19 1.000 0.664 View mutations
285 L 1 18 19 0.950 0.672 View mutations
286 F 1 18 19 0.953 0.729 View mutations
287 P 0 19 19 1.000 0.729 View mutations
288 F 3 16 19 0.832 0.673 View mutations
289 T 9 10 19 0.526 0.511 View mutations
290 H 0 19 19 0.998 0.731 View mutations
291 V 0 19 19 0.997 0.727 View mutations
292 K 1 18 19 0.938 0.549 View mutations
293 I 11 8 19 0.455 0.493 View mutations
294 F 4 15 19 0.798 0.441 View mutations
295 D 15 4 19 0.223 0.460 View mutations
296 P 19 0 19 0.010 0.548 View mutations
297 Q 16 3 19 0.162 0.547 View mutations
298 N 15 4 19 0.229 0.566 View mutations
299 P 11 8 19 0.470 0.457 View mutations
300 D 9 10 19 0.516 0.447 View mutations