P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 A 6 13 19 0.709 0.360 View mutations
227 I 18 1 19 0.086 0.783 View mutations
228 T 13 6 19 0.352 0.583 View mutations
229 P 0 19 19 0.997 0.212 View mutations
230 L 6 13 19 0.657 0.398 View mutations
231 P 10 9 19 0.457 0.454 View mutations
232 S 6 13 19 0.669 0.405 View mutations
233 T 2 17 19 0.882 0.408 View mutations
234 Q 2 17 19 0.852 0.427 View mutations
235 N 18 1 19 0.102 0.374 View mutations
236 G 19 0 19 0.014 0.480 View mutations
237 P 0 19 19 0.992 0.506 View mutations
238 V 1 18 19 0.930 0.516 View mutations
239 F 2 17 19 0.894 0.393 View mutations
240 A 8 11 19 0.629 0.512 View mutations
241 K 2 17 19 0.889 0.474 View mutations
242 A 1 18 19 0.914 0.551 View mutations
243 I 7 12 19 0.656 0.510 View mutations
244 Q 14 5 19 0.283 0.455 View mutations
245 K 3 16 19 0.811 0.568 View mutations
246 R 1 18 19 0.900 0.625 View mutations
247 V 3 16 19 0.851 0.627 View mutations
248 P 0 19 19 1.000 0.741 View mutations
249 C 1 18 19 0.947 0.623 View mutations
250 A 0 19 19 1.000 0.736 View mutations