P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 Y 0 19 19 1.000 0.714 View mutations
252 D 0 19 19 1.000 0.771 View mutations
253 K 0 19 19 0.999 0.683 View mutations
254 T 1 18 19 0.943 0.744 View mutations
255 A 0 19 19 1.000 0.795 View mutations
256 L 0 19 19 1.000 0.752 View mutations
257 A 0 19 19 1.000 0.670 View mutations
258 L 1 18 19 0.970 0.645 View mutations
259 E 0 19 19 0.982 0.612 View mutations
260 V 15 4 19 0.232 0.417 View mutations
261 G 0 19 19 0.999 0.698 View mutations
262 D 0 19 19 1.000 0.492 View mutations
263 I 5 14 19 0.787 0.419 View mutations
264 V 0 19 19 0.991 0.592 View mutations
265 K 12 7 19 0.371 0.409 View mutations
266 V 3 16 19 0.864 0.595 View mutations
267 T 0 19 19 0.994 0.576 View mutations
268 R 1 18 19 0.948 0.630 View mutations
269 M 1 18 19 0.935 0.633 View mutations
270 N 0 19 19 0.999 0.665 View mutations
271 I 3 16 19 0.829 0.591 View mutations
272 N 7 12 19 0.567 0.548 View mutations
273 G 0 19 19 0.984 0.751 View mutations
274 Q 0 19 19 1.000 0.716 View mutations
275 W 0 19 19 1.000 0.663 View mutations