P46109 (P46109)

Overview
Predicted structure (AF):
AF-P46109-F1-model_v4
Uniprot entry:
P46109
Gene:
P46109
Protein length:
303 residues
Mutations found:
5756
Benign based on D2Deep prediction:
2311 out of 5756 mutations
Pathogenic based on D2Deep prediction:
3445 out of 5756 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5756 mutations across 303 unique positions. There are 2311 benign and 3445 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 Q 0 19 19 1.000 0.664 View mutations
77 E 0 19 19 0.992 0.665 View mutations
78 F 0 19 19 1.000 0.700 View mutations
79 D 1 18 19 0.945 0.510 View mutations
80 H 3 16 19 0.827 0.380 View mutations
81 L 0 19 19 0.995 0.697 View mutations
82 P 1 18 19 0.924 0.541 View mutations
83 A 1 18 19 0.931 0.554 View mutations
84 L 1 18 19 0.903 0.769 View mutations
85 L 2 17 19 0.893 0.736 View mutations
86 E 15 4 19 0.239 0.350 View mutations
87 F 0 19 19 1.000 0.883 View mutations
88 Y 1 18 19 0.950 0.865 View mutations
89 K 4 15 19 0.767 0.653 View mutations
90 I 16 3 19 0.177 0.296 View mutations
91 H 3 16 19 0.853 0.775 View mutations
92 Y 4 15 19 0.690 0.704 View mutations
93 L 0 19 19 0.990 1.000 View mutations
94 D 0 19 19 1.000 0.863 View mutations
95 T 0 19 19 1.000 0.905 View mutations
96 T 0 19 19 0.995 0.867 View mutations
97 T 1 18 19 0.853 0.772 View mutations
98 L 19 0 19 0.009 0.198 View mutations
99 I 8 11 19 0.629 0.522 View mutations
100 E 13 6 19 0.292 0.454 View mutations