P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 L 0 19 19 0.999 0.781 View mutations
252 T 0 19 19 0.992 0.625 View mutations
253 S 1 18 19 0.940 0.514 View mutations
254 A 2 17 19 0.893 0.606 View mutations
255 D 0 19 19 1.000 0.634 View mutations
256 H 2 17 19 0.893 0.445 View mutations
257 L 0 19 19 0.993 0.748 View mutations
258 Y 1 18 19 0.933 0.617 View mutations
259 V 1 18 19 0.948 0.787 View mutations
260 N 0 19 19 0.988 0.685 View mutations
261 V 1 18 19 0.952 0.668 View mutations
262 S 0 19 19 1.000 0.658 View mutations
263 E 10 9 19 0.520 0.497 View mutations
264 L 7 12 19 0.670 0.508 View mutations
265 S 11 8 19 0.451 0.481 View mutations
266 L 5 14 19 0.694 0.547 View mutations
267 V 1 18 19 0.938 0.686 View mutations
268 N 5 14 19 0.760 0.581 View mutations
269 F 0 19 19 0.981 0.770 View mutations
270 E 0 19 19 0.989 0.716 View mutations
271 E 1 18 19 0.919 0.773 View mutations
272 S 1 18 19 0.916 0.761 View mutations
273 Q 8 11 19 0.594 0.537 View mutations
274 T 0 19 19 1.000 0.967 View mutations
275 F 1 18 19 0.947 0.873 View mutations