P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 S 11 8 19 0.438 0.498 View mutations
202 C 0 19 19 1.000 0.657 View mutations
203 N 18 1 19 0.048 0.499 View mutations
204 N 15 4 19 0.234 0.493 View mutations
205 L 9 10 19 0.509 0.502 View mutations
206 P 0 19 19 0.998 0.645 View mutations
207 L 0 19 19 0.998 0.724 View mutations
208 S 2 17 19 0.861 0.545 View mutations
209 H 1 18 19 0.870 0.695 View mutations
210 K 5 14 19 0.693 0.546 View mutations
211 V 3 16 19 0.824 0.667 View mutations
212 Y 5 14 19 0.683 0.514 View mutations
213 M 6 13 19 0.712 0.518 View mutations
214 R 1 18 19 0.882 0.485 View mutations
215 N 6 13 19 0.656 0.444 View mutations
216 S 7 12 19 0.610 0.437 View mutations
217 K 19 0 19 0.030 0.434 View mutations
218 Y 17 2 19 0.120 0.404 View mutations
219 P 19 0 19 0.025 0.430 View mutations
220 Q 19 0 19 0.033 0.393 View mutations
221 D 19 0 19 0.011 0.482 View mutations
222 L 19 0 19 0.047 0.456 View mutations
223 V 19 0 19 0.020 0.433 View mutations
224 M 14 5 19 0.322 0.424 View mutations
225 M 8 11 19 0.525 0.536 View mutations