P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 E 6 13 19 0.668 0.543 View mutations
227 G 9 10 19 0.564 0.507 View mutations
228 K 1 18 19 0.926 0.537 View mutations
229 M 0 19 19 0.978 0.575 View mutations
230 M 1 18 19 0.930 0.565 View mutations
231 S 4 15 19 0.789 0.578 View mutations
232 Y 0 19 19 1.000 0.657 View mutations
233 C 0 19 19 1.000 0.725 View mutations
234 T 0 19 19 0.995 0.598 View mutations
235 T 15 4 19 0.199 0.484 View mutations
236 G 12 7 19 0.410 0.462 View mutations
237 Q 11 8 19 0.445 0.484 View mutations
238 M 1 18 19 0.906 0.670 View mutations
239 W 0 19 19 0.986 0.753 View mutations
240 A 2 17 19 0.887 0.702 View mutations
241 R 3 16 19 0.845 0.644 View mutations
242 S 0 19 19 0.970 0.825 View mutations
243 S 2 17 19 0.885 0.794 View mutations
244 Y 2 17 19 0.896 0.821 View mutations
245 L 7 12 19 0.612 0.599 View mutations
246 G 0 19 19 1.000 0.908 View mutations
247 A 6 13 19 0.726 0.635 View mutations
248 V 1 18 19 0.955 0.823 View mutations
249 F 0 19 19 0.998 0.797 View mutations
250 N 1 18 19 0.956 0.701 View mutations