P48023 (FASLG)

Overview
Predicted structure (AF):
AF-P48023-F1-model_v4
Uniprot entry:
P48023
Gene:
FASLG
Protein length:
281 residues
Mutations found:
5338
Benign based on D2Deep prediction:
2681 out of 5338 mutations
Pathogenic based on D2Deep prediction:
2657 out of 5338 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5338 mutations across 281 unique positions. There are 2681 benign and 2657 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 N 17 2 19 0.178 0.691 View mutations
77 H 13 6 19 0.402 0.554 View mutations
78 S 2 17 19 0.837 0.297 View mutations
79 T 7 12 19 0.639 0.414 View mutations
80 G 2 17 19 0.907 0.325 View mutations
81 L 6 13 19 0.705 0.411 View mutations
82 C 6 13 19 0.719 0.412 View mutations
83 L 1 18 19 0.871 0.365 View mutations
84 L 14 5 19 0.261 0.456 View mutations
85 V 15 4 19 0.176 0.465 View mutations
86 M 8 11 19 0.485 0.433 View mutations
87 F 8 11 19 0.542 0.434 View mutations
88 F 16 3 19 0.158 0.416 View mutations
89 M 11 8 19 0.417 0.431 View mutations
90 V 10 9 19 0.465 0.432 View mutations
91 L 11 8 19 0.334 0.424 View mutations
92 V 15 4 19 0.237 0.391 View mutations
93 A 9 10 19 0.566 0.501 View mutations
94 L 11 8 19 0.434 0.496 View mutations
95 V 1 18 19 0.889 0.559 View mutations
96 G 11 8 19 0.380 0.494 View mutations
97 L 13 6 19 0.335 0.405 View mutations
98 G 15 4 19 0.231 0.455 View mutations
99 L 15 4 19 0.251 0.437 View mutations
100 G 8 11 19 0.558 0.507 View mutations