P49715 (CEBPA)

Overview
Predicted structure (AF):
AF-P49715-F1-model_v4
Uniprot entry:
P49715
Gene:
CEBPA
Protein length:
358 residues
Mutations found:
6801
Benign based on D2Deep prediction:
3331 out of 6801 mutations
Pathogenic based on D2Deep prediction:
3470 out of 6801 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 6801 mutations across 358 unique positions. There are 3331 benign and 3470 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
251 S 19 0 19 0.010 0.842 View mutations
252 A 19 0 19 0.003 0.840 View mutations
253 L 19 0 19 0.006 0.820 View mutations
254 K 19 0 19 0.002 0.879 View mutations
255 G 19 0 19 0.027 0.924 View mutations
256 L 16 3 19 0.193 0.784 View mutations
257 G 17 2 19 0.136 0.851 View mutations
258 A 19 0 19 0.051 0.902 View mutations
259 A 19 0 19 0.005 0.916 View mutations
260 H 19 0 19 0.040 0.898 View mutations
261 P 16 3 19 0.174 0.763 View mutations
262 D 10 9 19 0.558 0.505 View mutations
263 L 15 4 19 0.263 0.713 View mutations
264 R 17 2 19 0.132 0.806 View mutations
265 A 18 1 19 0.038 0.898 View mutations
266 S 18 1 19 0.109 0.918 View mutations
267 G 17 2 19 0.218 0.810 View mutations
268 G 19 0 19 0.030 0.918 View mutations
269 S 18 1 19 0.070 0.879 View mutations
270 G 17 2 19 0.181 0.781 View mutations
271 A 18 1 19 0.062 0.771 View mutations
272 G 17 2 19 0.114 0.629 View mutations
273 K 11 8 19 0.404 0.469 View mutations
274 A 7 12 19 0.637 0.429 View mutations
275 K 13 6 19 0.364 0.431 View mutations