P49715 (CEBPA)

Overview
Predicted structure (AF):
AF-P49715-F1-model_v4
Uniprot entry:
P49715
Gene:
CEBPA
Protein length:
358 residues
Mutations found:
6801
Benign based on D2Deep prediction:
3331 out of 6801 mutations
Pathogenic based on D2Deep prediction:
3470 out of 6801 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6801 mutations across 358 unique positions. There are 3331 benign and 3470 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 K 0 19 19 0.955 0.440 View mutations
277 S 14 5 19 0.264 0.448 View mutations
278 V 10 9 19 0.481 0.498 View mutations
279 D 1 18 19 0.912 0.603 View mutations
280 K 3 16 19 0.837 0.582 View mutations
281 N 4 15 19 0.790 0.564 View mutations
282 S 0 19 19 0.998 0.665 View mutations
283 N 0 19 19 0.999 0.603 View mutations
284 E 0 19 19 0.999 0.710 View mutations
285 Y 0 19 19 1.000 0.659 View mutations
286 R 0 19 19 1.000 0.708 View mutations
287 V 2 17 19 0.915 0.666 View mutations
288 R 0 19 19 1.000 0.709 View mutations
289 R 0 19 19 0.998 0.760 View mutations
290 E 0 19 19 0.999 0.855 View mutations
291 R 0 19 19 0.999 0.788 View mutations
292 N 0 19 19 1.000 0.813 View mutations
293 N 0 19 19 0.999 0.864 View mutations
294 I 0 19 19 0.991 0.909 View mutations
295 A 0 19 19 0.999 0.990 View mutations
296 V 0 19 19 1.000 0.896 View mutations
297 R 0 19 19 1.000 0.907 View mutations
298 K 0 19 19 1.000 0.861 View mutations
299 S 0 19 19 1.000 1.000 View mutations
300 R 0 19 19 1.000 0.925 View mutations