P49715 (CEBPA)

Overview
Predicted structure (AF):
AF-P49715-F1-model_v4
Uniprot entry:
P49715
Gene:
CEBPA
Protein length:
358 residues
Mutations found:
6801
Benign based on D2Deep prediction:
3331 out of 6801 mutations
Pathogenic based on D2Deep prediction:
3470 out of 6801 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6801 mutations across 358 unique positions. There are 3331 benign and 3470 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 D 0 19 19 0.991 0.944 View mutations
302 K 0 19 19 0.999 0.893 View mutations
303 A 0 19 19 1.000 0.950 View mutations
304 K 0 19 19 1.000 0.853 View mutations
305 Q 4 15 19 0.740 0.641 View mutations
306 R 0 19 19 1.000 0.900 View mutations
307 N 0 19 19 1.000 0.902 View mutations
308 V 11 8 19 0.468 0.444 View mutations
309 E 3 16 19 0.829 0.745 View mutations
310 T 0 19 19 1.000 0.933 View mutations
311 Q 0 19 19 0.996 0.840 View mutations
312 Q 13 6 19 0.286 0.426 View mutations
313 K 3 16 19 0.879 0.752 View mutations
314 V 0 19 19 1.000 0.883 View mutations
315 L 8 11 19 0.655 0.541 View mutations
316 E 7 12 19 0.595 0.585 View mutations
317 L 0 19 19 0.998 0.897 View mutations
318 T 2 17 19 0.866 0.692 View mutations
319 S 11 8 19 0.365 0.475 View mutations
320 D 0 19 19 0.975 0.843 View mutations
321 N 0 19 19 1.000 0.863 View mutations
322 D 2 17 19 0.924 0.729 View mutations
323 R 1 18 19 0.897 0.745 View mutations
324 L 0 19 19 1.000 0.984 View mutations
325 R 0 19 19 0.998 0.888 View mutations