P49715 (CEBPA)

Overview
Predicted structure (AF):
AF-P49715-F1-model_v4
Uniprot entry:
P49715
Gene:
CEBPA
Protein length:
358 residues
Mutations found:
6801
Benign based on D2Deep prediction:
3331 out of 6801 mutations
Pathogenic based on D2Deep prediction:
3470 out of 6801 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6801 mutations across 358 unique positions. There are 3331 benign and 3470 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 K 2 17 19 0.901 0.745 View mutations
327 R 0 19 19 0.997 0.892 View mutations
328 V 0 19 19 1.000 0.935 View mutations
329 E 0 19 19 0.998 0.892 View mutations
330 Q 0 19 19 0.998 0.792 View mutations
331 L 0 19 19 1.000 0.906 View mutations
332 S 1 18 19 0.957 0.763 View mutations
333 R 0 19 19 0.982 0.771 View mutations
334 E 0 19 19 1.000 0.999 View mutations
335 L 0 19 19 0.999 0.918 View mutations
336 D 0 19 19 0.984 0.825 View mutations
337 T 2 17 19 0.917 0.847 View mutations
338 L 0 19 19 0.995 0.967 View mutations
339 R 0 19 19 1.000 0.913 View mutations
340 G 3 16 19 0.800 0.774 View mutations
341 I 3 16 19 0.837 0.832 View mutations
342 F 0 19 19 1.000 0.990 View mutations
343 R 1 18 19 0.960 0.837 View mutations
344 Q 0 19 19 0.999 0.829 View mutations
345 L 1 18 19 0.949 0.926 View mutations
346 P 0 19 19 1.000 0.948 View mutations
347 E 1 18 19 0.959 0.832 View mutations
348 S 4 15 19 0.770 0.706 View mutations
349 S 2 17 19 0.888 0.800 View mutations
350 L 4 15 19 0.811 0.732 View mutations