P50148 (GNAQ)

Overview
Predicted structure (AF):
AF-P50148-F1-model_v4
Uniprot entry:
P50148
Gene:
GNAQ
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
4080 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2740 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 4080 benign and 2740 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 S 10 9 19 0.512 0.437 View mutations
327 H 3 16 19 0.820 0.630 View mutations
328 F 5 14 19 0.681 0.547 View mutations
329 T 0 19 19 0.987 0.851 View mutations
330 C 2 17 19 0.890 0.717 View mutations
331 A 0 19 19 1.000 0.902 View mutations
332 T 0 19 19 1.000 0.812 View mutations
333 D 4 15 19 0.771 0.626 View mutations
334 T 0 19 19 1.000 0.706 View mutations
335 E 14 5 19 0.270 0.473 View mutations
336 N 18 1 19 0.065 0.312 View mutations
337 I 18 1 19 0.097 0.349 View mutations
338 R 19 0 19 0.013 0.473 View mutations
339 F 19 0 19 0.000 0.352 View mutations
340 V 2 17 19 0.934 0.714 View mutations
341 F 19 0 19 0.000 0.332 View mutations
342 A 19 0 19 0.048 0.432 View mutations
343 A 7 12 19 0.560 0.529 View mutations
344 V 1 18 19 0.970 0.658 View mutations
345 K 19 0 19 0.000 0.454 View mutations
346 D 16 3 19 0.129 0.436 View mutations
347 T 9 10 19 0.561 0.501 View mutations
348 I 4 15 19 0.803 0.600 View mutations
349 L 16 3 19 0.137 0.445 View mutations
350 Q 19 0 19 0.024 0.440 View mutations