P50148 (GNAQ)

Overview
Predicted structure (AF):
AF-P50148-F1-model_v4
Uniprot entry:
P50148
Gene:
GNAQ
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
4080 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2740 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 4080 benign and 2740 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
301 D 19 0 19 0.002 0.499 View mutations
302 A 19 0 19 0.000 0.548 View mutations
303 Q 18 1 19 0.078 0.666 View mutations
304 A 11 8 19 0.485 0.456 View mutations
305 A 19 0 19 0.000 0.397 View mutations
306 R 19 0 19 0.001 0.567 View mutations
307 E 19 0 19 0.001 0.603 View mutations
308 F 19 0 19 0.006 0.389 View mutations
309 I 19 0 19 0.025 0.371 View mutations
310 L 15 4 19 0.225 0.468 View mutations
311 K 19 0 19 0.001 0.588 View mutations
312 M 19 0 19 0.000 0.583 View mutations
313 F 19 0 19 0.000 0.419 View mutations
314 V 19 0 19 0.008 0.568 View mutations
315 D 19 0 19 0.003 0.558 View mutations
316 L 19 0 19 0.000 0.559 View mutations
317 N 19 0 19 0.067 0.580 View mutations
318 P 19 0 19 0.000 0.553 View mutations
319 D 19 0 19 0.062 0.608 View mutations
320 S 19 0 19 0.011 0.628 View mutations
321 D 19 0 19 0.020 0.573 View mutations
322 K 15 4 19 0.256 0.423 View mutations
323 I 19 0 19 0.000 0.541 View mutations
324 I 2 17 19 0.917 0.476 View mutations
325 Y 2 17 19 0.893 0.610 View mutations