P50148 (GNAQ)

Overview
Predicted structure (AF):
AF-P50148-F1-model_v4
Uniprot entry:
P50148
Gene:
GNAQ
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
4080 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2740 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 4080 benign and 2740 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
276 K 5 14 19 0.721 0.514 View mutations
277 D 19 0 19 0.003 0.204 View mutations
278 L 19 0 19 0.009 0.235 View mutations
279 L 10 9 19 0.525 0.489 View mutations
280 E 18 1 19 0.086 0.472 View mutations
281 E 1 18 19 0.948 0.599 View mutations
282 K 3 16 19 0.785 0.660 View mutations
283 I 6 13 19 0.662 0.584 View mutations
284 M 10 9 19 0.471 0.442 View mutations
285 Y 16 3 19 0.240 0.423 View mutations
286 S 19 0 19 0.008 0.270 View mutations
287 H 18 1 19 0.032 0.365 View mutations
288 L 1 18 19 0.947 0.709 View mutations
289 V 18 1 19 0.050 0.499 View mutations
290 D 9 10 19 0.533 0.503 View mutations
291 Y 6 13 19 0.641 0.534 View mutations
292 F 1 18 19 0.957 0.682 View mutations
293 P 19 0 19 0.000 0.313 View mutations
294 E 13 6 19 0.307 0.500 View mutations
295 Y 19 0 19 0.001 0.402 View mutations
296 D 19 0 19 0.000 0.453 View mutations
297 G 1 18 19 0.928 0.597 View mutations
298 P 15 4 19 0.179 0.420 View mutations
299 Q 18 1 19 0.075 0.468 View mutations
300 R 18 1 19 0.072 0.566 View mutations