P50148 (GNAQ)

Overview
Predicted structure (AF):
AF-P50148-F1-model_v4
Uniprot entry:
P50148
Gene:
GNAQ
Protein length:
359 residues
Mutations found:
6820
Benign based on D2Deep prediction:
4080 out of 6820 mutations
Pathogenic based on D2Deep prediction:
2740 out of 6820 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 6820 mutations across 359 unique positions. There are 4080 benign and 2740 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 Q 17 2 19 0.122 0.476 View mutations
177 Q 11 8 19 0.432 0.477 View mutations
178 D 1 18 19 0.954 0.741 View mutations
179 V 4 15 19 0.792 0.658 View mutations
180 L 2 17 19 0.906 0.690 View mutations
181 R 15 4 19 0.283 0.420 View mutations
182 V 8 11 19 0.540 0.517 View mutations
183 R 1 18 19 0.943 0.622 View mutations
184 V 12 7 19 0.390 0.493 View mutations
185 P 18 1 19 0.063 0.415 View mutations
186 T 19 0 19 0.031 0.280 View mutations
187 T 3 16 19 0.804 0.646 View mutations
188 G 1 18 19 0.849 0.656 View mutations
189 I 1 18 19 0.921 0.643 View mutations
190 I 14 5 19 0.303 0.398 View mutations
191 E 1 18 19 0.932 0.592 View mutations
192 Y 12 7 19 0.394 0.489 View mutations
193 P 14 5 19 0.349 0.422 View mutations
194 F 13 6 19 0.307 0.484 View mutations
195 D 18 1 19 0.096 0.573 View mutations
196 L 18 1 19 0.053 0.456 View mutations
197 Q 19 0 19 0.015 0.544 View mutations
198 S 11 8 19 0.404 0.486 View mutations
199 V 17 2 19 0.105 0.477 View mutations
200 I 7 12 19 0.614 0.423 View mutations