P58012 (P58012)

Overview
Predicted structure (AF):
AF-P58012-F1-model_v4
Uniprot entry:
P58012
Gene:
P58012
Protein length:
376 residues
Mutations found:
7143
Benign based on D2Deep prediction:
4360 out of 7143 mutations
Pathogenic based on D2Deep prediction:
2783 out of 7143 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7143 mutations across 376 unique positions. There are 4360 benign and 2783 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 T 0 19 19 1.000 0.739 View mutations
77 L 0 19 19 1.000 0.759 View mutations
78 S 0 19 19 0.999 0.727 View mutations
79 G 0 19 19 0.997 0.723 View mutations
80 I 0 19 19 0.998 0.727 View mutations
81 Y 0 19 19 0.986 0.713 View mutations
82 Q 0 19 19 0.999 0.608 View mutations
83 Y 1 18 19 0.941 0.610 View mutations
84 I 1 18 19 0.908 0.699 View mutations
85 I 3 16 19 0.749 0.616 View mutations
86 A 12 7 19 0.405 0.488 View mutations
87 K 8 11 19 0.574 0.519 View mutations
88 F 3 16 19 0.803 0.717 View mutations
89 P 8 11 19 0.572 0.555 View mutations
90 F 7 12 19 0.548 0.566 View mutations
91 Y 2 17 19 0.812 0.758 View mutations
92 E 13 6 19 0.358 0.390 View mutations
93 K 12 7 19 0.320 0.452 View mutations
94 N 15 4 19 0.314 0.316 View mutations
95 K 9 10 19 0.449 0.513 View mutations
96 K 15 4 19 0.311 0.344 View mutations
97 G 18 1 19 0.185 0.147 View mutations
98 W 6 13 19 0.539 0.645 View mutations
99 Q 13 6 19 0.298 0.339 View mutations
100 N 4 15 19 0.780 0.741 View mutations