P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
451 R 19 0 19 0.019 0.489 View mutations
452 L 10 9 19 0.483 0.498 View mutations
453 D 15 4 19 0.226 0.425 View mutations
454 A 19 0 19 0.005 0.444 View mutations
455 L 16 3 19 0.151 0.374 View mutations
456 W 14 5 19 0.282 0.409 View mutations
457 A 8 11 19 0.544 0.515 View mutations
458 L 14 5 19 0.295 0.464 View mutations
459 L 15 4 19 0.282 0.489 View mutations
460 R 17 2 19 0.083 0.462 View mutations
461 R 19 0 19 0.028 0.418 View mutations
462 Q 12 7 19 0.457 0.466 View mutations
463 Y 14 5 19 0.235 0.428 View mutations
464 D 19 0 19 0.027 0.314 View mutations
465 R 7 12 19 0.603 0.525 View mutations
466 V 15 4 19 0.237 0.397 View mutations
467 S 10 9 19 0.525 0.497 View mutations
468 L 19 0 19 0.028 0.416 View mutations
469 M 3 16 19 0.835 0.574 View mutations
470 R 1 18 19 0.935 0.565 View mutations
471 P 0 19 19 1.000 0.607 View mutations
472 Q 19 0 19 0.026 0.439 View mutations
473 E 19 0 19 0.001 0.404 View mutations
474 G 16 3 19 0.200 0.382 View mutations
475 D 4 15 19 0.762 0.521 View mutations