P58335-4 (P58335-4)

Overview
Predicted structure (AF):
AF-P58335-4-F1-model_v4
Uniprot entry:
P58335-4
Gene:
P58335-4
Protein length:
488 residues
Mutations found:
9271
Benign based on D2Deep prediction:
5560 out of 9271 mutations
Pathogenic based on D2Deep prediction:
3711 out of 9271 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9271 mutations across 488 unique positions. There are 5560 benign and 3711 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
426 I 16 3 19 0.152 0.537 View mutations
427 R 15 4 19 0.196 0.499 View mutations
428 P 10 9 19 0.484 0.455 View mutations
429 R 19 0 19 0.141 0.569 View mutations
430 P 18 1 19 0.073 0.605 View mutations
431 P 19 0 19 0.031 0.660 View mutations
432 R 18 1 19 0.059 0.629 View mutations
433 P 19 0 19 0.000 0.663 View mutations
434 K 19 0 19 0.025 0.699 View mutations
435 P 19 0 19 0.001 0.603 View mutations
436 T 19 0 19 0.001 0.599 View mutations
437 H 19 0 19 0.000 0.652 View mutations
438 Q 17 2 19 0.145 0.582 View mutations
439 P 19 0 19 0.008 0.588 View mutations
440 P 17 2 19 0.128 0.565 View mutations
441 Q 14 5 19 0.204 0.489 View mutations
442 T 19 0 19 0.003 0.498 View mutations
443 K 19 0 19 0.001 0.496 View mutations
444 W 8 11 19 0.540 0.514 View mutations
445 Y 15 4 19 0.295 0.434 View mutations
446 T 19 0 19 0.001 0.340 View mutations
447 P 7 12 19 0.572 0.548 View mutations
448 I 16 3 19 0.199 0.403 View mutations
449 K 14 5 19 0.222 0.458 View mutations
450 G 8 11 19 0.532 0.523 View mutations